Author

R. Brinkschulte

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Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

C. Engel· 1 shared E. Latz· 1 shared G. Hagelueken· 1 shared I. V. Hochheiser· 1 shared J. Moecking· 1 shared M. Geyer· 1 shared M. Marleaux· 1 shared M. Pilsl· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

C. Engel

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1 paper

Recent·Most cited

Cryo-EM structure of the NLRP3 decamer bound to the cytokine release inhibitory drug CRID3

I. V. Hochheiser, M. Pilsl, G. Hagelueken, J. Moecking, M. Marleaux, R. Brinkschulte, E. Latz, C. Engel, M. Geyer

The paper determines the cryo-EM structure of NLRP3 bound to CRID3, revealing how the inhibitor stabilizes the protein and provides insights for drug development.

bioRxiv · Jul 22, 2021Immunology