Cancer BiologybioRxivPreprint
A Focused Small-Molecule Screen Identifies PHA-680626 as an Amphosteric Inhibitor Disrupting the Interaction between Aurora-A and N-Myc
F. Souvalidou, D. Boi, R. Montanari…·A. Paiardini
This study identifies PHA-680626 as an amphosteric inhibitor that disrupts the AURKA/N-Myc interaction, reducing N-Myc levels and cell viability in neuroblastoma cells.
DOI 10.1101/2021.03.10.433854