Loss of TMEM65 causes mitochondrial disease mediated by mitochondrial calcium
Y. Zhang, L. Reyes, J. Sun, C. Liu, D. Springer, A. C. Noguchi, A. M. Aponte, J. Munasinghe, R. Covian, E. Murphy, B. Glancy
This study identifies TMEM65's role in mitochondrial calcium regulation, showing its loss causes mitochondrial disease and suggesting therapeutic targeting of mitochondrial calcium as a potential treatment.
bioRxiv · Aug 2, 2022 · PreprintPhysiology