Enhancing Uterine Receptivity for Embryo Implantation through Controlled Collagenase Intervention
E. Zehorai, T. Gross, E. Shimshoni, R. Hadas, I. Adir, O. Golani, G. Molodij, R. Eitan, K. Kadler, O. Kollet, M. Neeman, N. Dakel, I. Solomonov, I. Sagi
This paper shows that collagenase-1 treatment improves embryo implantation in mice by remodeling the endometrial ECM and enhancing vascular permeability and NK cell infiltration, with potential applications in human reproduction.
bioRxiv · Jan 18, 2022Biochemistry