The essential role of hypermutation in rapid adaptation to antibiotic stress
H. H. Mehta, A. G. Prater, K. Beabout, R. Elworth, M. Karavis, H. S. Gibbons, Y. Shamoo
This study examines hypermutation's role in Pseudomonas aeruginosa adaptation to colistin, identifying adaptive mutations and highlighting the risk of re-infection from susceptible cells.
bioRxiv · Sep 20, 2018Evolutionary Biology