R. Esposito

Cell type specific long non-coding RNA targets identified by integrative analysis of single-cell and bulk colorectal cancer transcriptomes

The paper identifies cell type-specific lncRNAs in CRC using single-cell and bulk transcriptomes, showing their enrichment in epithelial cells and validating their role in CRC proliferation.

Mutational effects on carbapenem hydrolysis of YEM-1, a new sub-class B2 metallo-β-lactamase from Yersinia mollaretii

The paper characterizes YEM-1, a new subclass B2 metallo-β-lactamase from Yersinia mollaretii, showing it hydrolyzes only imipenem efficiently and identifies key residues responsible for its substrate specificity.