Author

P. Chouvardas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Pharmacology & Toxicology· 1

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. Tzaferis· 3 shared G. Kollias· 3 shared A. Prados· 2 shared D. Papadopoulou· 2 shared F. Roumelioti· 2 shared M. Denis· 2 shared N. Karagianni· 2 shared A. Henriques· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

C. Tzaferis

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell type specific long non-coding RNA targets identified by integrative analysis of single-cell and bulk colorectal cancer transcriptomes

A. Mihaljevic, P. Rubin, P. Chouvardas, R. Esposito

The paper identifies cell type-specific lncRNAs in CRC using single-cell and bulk transcriptomes, showing their enrichment in epithelial cells and validating their role in CRC proliferation.

bioRxiv · Jan 8, 2024Cancer Biology

Identifying drug sensitivity of multifocal primary prostate cancer

J. Kang, P. Chouvardas, K. Ovchinnikova, G. N. Thalmann, S. Karkampouna, M. Kruithof-de Julio

This study uses patient-derived organoids to investigate drug sensitivity in multifocal prostate cancer and develops a transcriptomics-based model to predict drug responses.

bioRxiv · Dec 12, 2023 · PreprintCancer Biology

Repurposing of Amisulpride, a known antipsychotic drug, to target synovial fibroblasts activation in arthritis.

D. Papadopoulou, F. Roumelioti, C. Tzaferis, P. Chouvardas, A.-K. Pedersen, F. Charalampous, E. Christodoulou-Vafeiadou, L. Ntari, N. Karagianni, M. Denis, J. V. Olsen, A. N. Matralis, G. Kollias

This study identifies Amisulpride as a potential therapeutic for arthritis by reducing synovial fibroblast activation, independent of its known targets.

bioRxiv · Aug 2, 2022 · PreprintPharmacology & Toxicology

miR-221/222 drive synovial fibroblast expansion and pathogenesis of TNF-mediated arthritis

F. Roumelioti, C. Tzaferis, D. Konstantopoulos, D. Papadopoulou, A. Prados, M. Sakkou, A. Liakos, P. Chouvardas, T. Meletakos, Y. Pandis, N. Karagianni, M. Denis, M. Fousteri, M. Armaka, G. Kollias

This study shows miR-221/222 promotes synovial fibroblast expansion and worsens TNF-mediated arthritis by regulating cell cycle and ECM pathways.

bioRxiv · Jul 22, 2022 · PreprintCell Biology

Col6a1+/CD201+ mesenchymal cells regulate intestinal morphogenesis and homeostasis

M.-T. Melissari, A. Henriques, C. Tzaferis, A. Prados, M. E. Sarris, P. Chouvardas, S. Grammenoudi, G. Kollias, V. Koliaraki

The paper identifies and characterizes Col6a1+/CD201+ mesenchymal cells in the intestine, showing their role in morphogenesis, homeostasis, and plasticity during inflammation.

bioRxiv · Feb 16, 2021Cell Biology