The combination of mitogenic stimulation and cell cycle arrest induces senescence in equine and human cartilage explants
M. E. Copp, M. C. Flanders, R. Gagliardi, J. M. Gilbertie, G. A. Sessions, S. Chubinskaya, R. F. Loeser, L. V. Schnabel, B. O. Diekman
This study induces senescence in equine and human cartilage explants by combining mitogenic stimulation with cell cycle arrest, showing increased SA-β-gal activity.
bioRxiv · Mar 5, 2020Cell Biology