R. Fernandez-Gonzalez

mTOR inhibits autophagy to facilitate cell swelling and rapid wound repair

This study shows that mTORC1 inhibits autophagy to enable cell swelling, which accelerates embryonic wound repair.

Cortical tension regulates Hippo signaling via Par-1-mediated Kibra degradation

This study shows cortical tension modulates Hippo signaling by affecting Kibra degradation through Par-1.

Integrin-based adhesions promote cell-cell junction remodelling and cytoskeletal rearrangements to drive embryonic wound healing

This study shows integrin-based adhesions facilitate cell-cell junction remodeling and cytoskeletal rearrangements during embryonic wound healing in Drosophila.

Rap1 coordinates cell-cell adhesion and cytoskeletal reorganization to drive collective cell migration in vivo

This study identifies Rap1's role in coordinating cell-cell adhesion and cytoskeletal reorganization during collective cell migration in Drosophila embryos.

The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium

This study shows Rab25 coordinates cytokinetic bridge abscission and cortical actin density in zebrafish gastrula epithelium, affecting cell shape and tissue-scale forces during epiboly.

Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex

This study shows that Pak1 and PP2A counteract aPKC to maintain cortical tension via Yurt, supporting epithelial cell polarization and tissue architecture.

The Crk adapter protein is essential for Drosophila embryogenesis, where it regulates multiple actin-dependent morphogenic events

This study shows Crk is essential for Drosophila embryogenesis, regulating actin dynamics in mitosis, wound healing, and axon patterning.