Author

R. Hallal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Tempe· 2 shared G. Bossis· 2 shared G. Cartron· 2 shared L. Gabellier· 2 shared M. De Toledo· 2 shared C. Recher· 1 shared D. Gitenay· 1 shared E. Gueret· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

D. Tempe

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2 papers

Recent·Most cited

The SUMOylation inhibitor TAK-981 (Subasumstat) triggers IFN-I-dependent activation of Natural Killer cells against Acute Myeloid Leukemias.

R. Hallal, M. De Toledo, D. Tempe, S. Zemiti, L. Coenon, D. Gitenay, S. George, S. Bonnet, L. Gabellier, G. Cartron, M. Pelegrin, M. Villalba, G. Bossis

This paper shows that TAK-981 activates NK cells against AML by inducing IFN-I secretion, enhancing their cytotoxicity and cytokine production.

bioRxiv · Feb 19, 2024 · PreprintCancer Biology

The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of Acute Myeloid Leukemias

R. Paolillo, M. Boulanger, P. Gatel, L. Gabellier, D. Tempe, R. Hallal, M. De Toledo, J. Moreaux, H. Baik, E. Gueret, C. Recher, J.-E. Sarry, G. Cartron, M. Piechaczyk, G. Bossis

This study identifies NOX2 as a marker of poor prognosis and a contributor to chemoresistance in AML, showing its upregulation in drug-resistant cells and association with adverse outcomes.

bioRxiv · Mar 4, 2021Cancer Biology