Patient-derived response estimates from zero-passage organoids of luminal breast cancer
R. Przanowska, N. Labban, P. Przanowski, R. Hawes, K. Atkins, S. Showalter, K. Janes
This study develops zero-passage organoids from luminal breast cancer patient samples to test genetic and pharmacologic perturbations, finding variable hormone responsiveness and complex interactions with sulforaphane and NQO1 knockout.
bioRxiv · Mar 24, 2024 · PreprintCancer Biology