Adhesion of Crithidia fasciculata promotes a rapid change in developmental fate driven by cAMP signaling
S. Denecke, M. F. Malfara, K. R. Hodges, N. A. Holmes, A. R. Williams, J. H. Gallagher-Teske, J. M. Pascarella, A. M. Daniels, G. J. Sterk, R. Leurs, G. Ruthel, R. Hoang, M. L. Povelones, M. Povelones
This study investigates how adhesion triggers differentiation in Crithidia fasciculata, showing cAMP signaling is critical for attachment and involves reorganization of signaling components along the flagellum.
bioRxiv · Oct 6, 2022Microbiology