Author

R. Hotta

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. J. Murphy· 1 shared A. M. Goldstein· 1 shared J. L. Mueller· 1 shared K. Cornejo· 1 shared N. Picard· 1 shared R. Guyer· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

A. J. Murphy

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1 paper

Recent·Most cited

Differentiated neuroblastoma cells remain epigenetically poised for de-differentiation to an immature state

R. Guyer, N. Picard, J. L. Mueller, A. J. Murphy, K. Cornejo, R. Hotta, A. M. Goldstein

This study shows neuroblastoma cells can switch between a neuronal gene expression state and a de-differentiated state, with CD49b marking proliferative immature cells and CD49b-negative cells capable of generating tumors.

bioRxiv · Jul 10, 2022Cancer Biology