A mutation in the pmrD gene of Shigella flexneri abrogates functional PhoPQ-PmrD-PmrAB signaling and polymyxin B resistance
The paper identifies a frameshift mutation in the pmrD gene of S. flexneri that disrupts PhoPQ-PmrD-PmrAB signaling and polymyxin B resistance, contrasting with S. sonnei's functional PmrD.
bioRxiv · Jul 26, 2021 · PreprintMicrobiology