Author

R. Irwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Hofmann· 1 shared I. Petrovic· 1 shared O. Faust· 1 shared R. Rosenzweig· 1 shared S. G. Wolf· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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1 shared paperBiophysics

H. Hofmann

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1 paper

Recent·Most cited

Hsp40s display class-specific binding profiles, serving complementary roles in the prevention of tau amyloid formation

R. Irwin, O. Faust, I. Petrovic, S. G. Wolf, H. Hofmann, R. Rosenzweig

This study shows DNAJA2 and DNAJB1 prevent tau amyloid formation by binding distinct tau species, while HSPB1 only binds monomers, revealing complementary roles of Hsp40 chaperones in tau aggregation prevention.

bioRxiv · Apr 11, 2021 · PreprintBiophysics