Author

R. J. Mulligan

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Cell Biology· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Winckler· 1 shared C. C. Yap· 1 shared L. Digilio· 1 shared M. M. Magaj· 1 shared S. Redemann· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

B. Winckler

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1 paper

Recent·Most cited

Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

R. J. Mulligan, M. M. Magaj, L. Digilio, S. Redemann, C. C. Yap, B. Winckler

The paper shows that neutralizing late endosomal pH via LLOMe or NH4Cl hyper-activates Rab7 through V-ATPase and RILP, disrupting tubulation and CI-M6PR trafficking.

bioRxiv · Oct 24, 2023Cell Biology