Sem1/DSS1 accelerates ATP-dependent substrate unfolding by the proteasome through a conformation-dependent intercomplex contact
R. J. Tomko, R. G. Reed, G. W. Jobin
This study shows Sem1/DSS1 enhances ATP-dependent substrate unfolding by the proteasome through a conformation-dependent intercomplex contact, despite being a small, unstructured subunit.
bioRxiv · Jun 27, 2022 · PreprintBiochemistry