Author

R. Jauch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

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Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Hutchins· 2 shared G. Ma· 2 shared H. Hu· 2 shared L. Shi· 2 shared L. Sun· 2 shared X. Fu· 2 shared Z. Xiao· 2 shared B. Deng· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

A. Hutchins

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2 papers

Recent·Most cited

BRD8 guards the pluripotent state by sensing and maintaining histone acetylation

L. Sun, X. Fu, Z. Xiao, G. Ma, Y. Zhou, H. Hu, L. Shi, D. Li, R. Jauch, A. Hutchins

This study shows BRD8 maintains pluripotency by sensing and maintaining histone acetylation, preventing the conversion of primed EpiSCs to naive ESCs.

bioRxiv · Mar 20, 2024Cell Biology

Modulating the epigenetic state promotes the reprogramming of transformed cells to pluripotency in a line-specific manner

X. Fu, Q. Zhuang, I. A. Babarinde, L. Shi, G. Ma, H. Hu, Y. Li, J. Chen, Z. Xiao, B. Deng, L. Sun, R. Jauch, A. Hutchins

This study identifies line-specific barriers to reprogramming transformed cells and shows that MEK inhibition can overcome some of these barriers by modulating the epigenetic state.

bioRxiv · Dec 1, 2022 · PreprintCell Biology