Loss of FBXO9 enhances proteasome activity and promotes aggressiveness in acute myeloid leukemia
R. W. Hynes-Smith, S. A. Swenson, H. Vahle, K. J. Wittorf, M. Caplan, C. Amador, R. K. Hyde, S. M. Buckley
This study shows loss of FBXO9 increases proteasome activity and promotes aggressiveness in AML, suggesting potential for bortezomib treatment response prediction.
bioRxiv · Aug 12, 2019Cancer Biology