Author

H. Vahle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. W. Hynes-Smith· 2 shared S. A. Swenson· 2 shared S. M. Buckley· 2 shared C. Amador· 1 shared H. C. H. Law· 1 shared K. J. Wittorf· 1 shared M. Caplan· 1 shared M. R. Green· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

R. W. Hynes-Smith

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2 papers

Recent·Most cited

E3 Ligase UBR5 HECT domain mutations in lymphoma control maturation of B cells via alternative splicing

S. A. Swenson, T. J. Gilbreath, H. Vahle, R. W. Hynes-Smith, H. C. H. Law, N. T. Woods, M. R. Green, S. M. Buckley

This study shows that UBR5 HECT domain mutations in lymphoma disrupt B cell maturation by altering alternative splicing, suggesting a role in mantle cell lymphoma initiation.

bioRxiv · Aug 12, 2019 · PreprintImmunology

Loss of FBXO9 enhances proteasome activity and promotes aggressiveness in acute myeloid leukemia

R. W. Hynes-Smith, S. A. Swenson, H. Vahle, K. J. Wittorf, M. Caplan, C. Amador, R. K. Hyde, S. M. Buckley

This study shows loss of FBXO9 increases proteasome activity and promotes aggressiveness in AML, suggesting potential for bortezomib treatment response prediction.

bioRxiv · Aug 12, 2019Cancer Biology