Chemical-induced degradation of PreS2 mutant surface antigen reverses HBV- mediated hepatocarcinogenesis
J. Y. Yang, Y.-H. Wu, M. Y.-C. Pan, Y.-T. Chiou, R. K.-L. Lee, T.-N. Li, L. Wang
This study identifies ABT199 as an inhibitor of PreS2-LHBS that reverses HBV-mediated hepatocarcinogenesis through microautophagy-induced degradation.
bioRxiv · Jan 24, 2022 · PreprintMicrobiology