A high-throughput fluorescence polarization assay to discover inhibitors of arenavirus and coronavirus exoribonucleases
S. G. Hernandez Tapia, M. Feracci, C. T. De Jesus, P. El-Kazzi, R. Kaci, L. Garlatti, E. Decroly, B. Canard, F. Ferron, K. Alvarez
This paper develops a high-throughput fluorescence polarization assay to screen inhibitors of exoribonucleases from arenaviruses and coronaviruses and validates it with a small compound library.
bioRxiv · Apr 2, 2021 · PreprintBiochemistry