Inhibition of USP28 overcomes Cisplatin-Resistance of Squamous Tumors by Suppression of the Fanconi Anemia Pathway.
C. Prieto-Garcia, O. Hartmann, M. Reissland, T. Fischer, C. R. Maier, M. Rosenfeldt, C. Schuelein-Voelk, K. Klann, R. Kalb, I. Dikic, C. Muench, M. E. Diefenbacher
This study identifies USP28 inhibition as a strategy to overcome cisplatin resistance in squamous cell carcinomas by suppressing the Fanconi Anemia DNA repair pathway.
bioRxiv · Sep 10, 2020Cancer Biology