Author

R. Kouyos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:mixed model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Calmy· 1 shared A. Marzel· 1 shared A. Rauch· 1 shared A. Scherrer· 1 shared E. Bernasconi· 1 shared F. Bertels· 1 shared G. Leventhal· 1 shared G. Van Zyl· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperEvolutionary Biology

A. Calmy

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2 papers

Recent·Most cited

Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C

S. Posada-Cespedes, G. Van Zyl, H. Montazeri, J. Kuipers, S.-Y. Rhee, R. Kouyos, H. F. Günthard, N. Beerenwinkel

This paper compares mutational pathways to lopinavir resistance in HIV-1 subtypes B and C using a probabilistic model, finding distinct initial mutations and diverse evolutionary pathways.

bioRxiv · Sep 25, 2020Evolutionary Biology

Dissecting HIV Virulence: Heritability Of Setpoint Viral Load, CD4+ T Cell Decline And Per-Parasite Pathogenicity

F. Bertels, A. Marzel, G. Leventhal, V. Mitov, J. Fellay, H. F. Gunthard, J. Boni, S. Yerly, T. Klimkait, V. Aubert, M. Battegay, A. Rauch, M. Cavassini, A. Calmy, E. Bernasconi, , Swiss HIV Cohort Study

The paper estimates heritability of HIV virulence traits using donor-recipient regression and phylogenetic models, finding moderate heritability for CD4+ T cell decline and per-parasite pathogenicity.

bioRxiv · Sep 8, 2017Evolutionary Biology