Author

T. Klimkait

University of Basel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 1 Genetic & Genomic Medicine· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:mixed model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Rauch· 2 shared E. Bernasconi· 2 shared M. Battegay· 2 shared M. Cavassini· 2 shared P. Schmid· 2 shared S. Yerly· 2 shared A. Anagnostopoulos· 1 shared A. Calmy· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

A. Rauch

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Increased CHIP Prevalence Amongst People Living with HIV

Alexander G. Bick, Konstantin Popadin, Christian W. Thorball, Md Mesbah Uddin, Markella V. Zanni, Bing Yu, Matthias Cavassini, Andri Rauch, Philip Tarr, Patrick Schmid, Enos Bernasconi, Huldrych F. Günthard, Peter Libby, Eric Boerwinkle, Paul J. McLaren, , S. Yerly

The paper investigates the prevalence of clonal hematopoiesis of indeterminate potential (CHIP) in people living with HIV and finds a higher prevalence compared to controls.

Scientific Reports · Jan 12, 2022Peer-reviewedGenetic & Genomic Medicine

The Petasites hybridus CO2-extract (Ze 339) blocks SARS-CoV-2 replication in vitro

L. Urda, M. Kreuter, J. Drewe, G. Boonen, V. Butterweck, T. Klimkait

This study evaluates the anti-SARS-CoV-2 activity of Petasites hybridus CO2-extract (Ze 339) and its major compounds, showing potent in vitro inhibition of both Wuhan and Delta variants.

bioRxiv · Dec 3, 2021Pharmacology & Toxicology

Dissecting HIV Virulence: Heritability Of Setpoint Viral Load, CD4+ T Cell Decline And Per-Parasite Pathogenicity

F. Bertels, A. Marzel, G. Leventhal, V. Mitov, J. Fellay, H. F. Gunthard, J. Boni, S. Yerly, T. Klimkait, V. Aubert, M. Battegay, A. Rauch, M. Cavassini, A. Calmy, E. Bernasconi, , Swiss HIV Cohort Study

The paper estimates heritability of HIV virulence traits using donor-recipient regression and phylogenetic models, finding moderate heritability for CD4+ T cell decline and per-parasite pathogenicity.

bioRxiv · Sep 8, 2017Evolutionary Biology