Author

R. L. Gourse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1

Frequent Co-Authors

E. A. Campbell· 2 shared S. A. Darst· 2 shared W. Ross· 2 shared A. B. Banta· 1 shared A. J. Cartagena· 1 shared A. Y. Chen· 1 shared C. Chiu· 1 shared J. Chen· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

E. A. Campbell

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2 papers

Recent·Most cited

E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation and dynamics

J. Chen, S. Gopalkrishnan, C. Chiu, A. Y. Chen, E. A. Campbell, R. L. Gourse, W. Ross, S. A. Darst

This study shows TraR regulates transcription by altering RNAP conformation and dynamics, affecting promoter DNA interactions and transcription outcomes.

bioRxiv · Sep 12, 2019Biophysics

Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase

A. J. Cartagena, A. B. Banta, N. Sathyan, W. Ross, R. L. Gourse, E. A. Campbell, S. A. Darst

The paper determines the cryo-EM structure of Crl-σS-RNAP complex and shows Crl stabilizes σS-RNAP by tethering σS to RNAP βCT.

bioRxiv · Aug 6, 2019Biophysics