Author

A. J. Cartagena

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

S. A. Darst· 2 shared A. B. Banta· 1 shared A. J. Link· 1 shared A. L. Manson· 1 shared A. M. Earl· 1 shared D. V. Carson· 1 shared E. A. Campbell· 1 shared J. D. Chen· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

S. A. Darst

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery, Characterization, and Bioactivity of the Achromonodins: Lasso Peptides Encoded by Achromobacter

D. V. Carson, Y. Zhang, L. So, W. L. Cheung-Lee, A. J. Cartagena, S. A. Darst, A. J. Link

The paper discovers and characterizes two lasso peptides from Achromobacter species, showing one inhibits RNA polymerase and has antimicrobial activity against Achromobacter pulmonis.

bioRxiv · Jun 21, 2023Biochemistry

The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales

A. J. Cartagena, K. L. Taylor, L. C. Lopez, J. Su, J. T. Smith, A. L. Manson, J. D. Chen, V. M. Pierce, A. M. Earl, R. P. Bhattacharyya

This study shows that carbapenemase-producing CRE exhibit an inoculum effect, which can mislead susceptibility testing and highlights the need for improved detection methods.

bioRxiv · May 23, 2023 · PreprintMicrobiology

Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase

A. J. Cartagena, A. B. Banta, N. Sathyan, W. Ross, R. L. Gourse, E. A. Campbell, S. A. Darst

The paper determines the cryo-EM structure of Crl-σS-RNAP complex and shows Crl stabilizes σS-RNAP by tethering σS to RNAP βCT.

bioRxiv · Aug 6, 2019Biophysics