Cre/LoxP-HBV plasmids generating recombinant covalently closed circular DNA genome upon transfection
R. L. Kruse, X. Legras, M. Barzi
This paper develops recombinant circular HBV genomes (rcccDNA) using Cre/LoxP technology to better model cccDNA for HBV therapy research.
bioRxiv · Jul 21, 2020Microbiology