Human-derived NLS enhance the gene transfer efficiency of chitosan
D. B. Bitoque, J. Morais, A. V. Oliveira, R. L. Sequeira, S. M. Calado, T. M. Fortunato, S. Simao, A. M. Rosa da Costa, G. A. Silva
This study tests human-derived NLS peptides to enhance chitosan-based non-viral gene delivery efficiency, finding a 2-fold increase with co-complexation and covalent ligation.
bioRxiv · Mar 13, 2020Bioengineering