Author

R. M. Betz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. C. Kruse· 1 shared H. R. Schmidt· 1 shared R. O. Dror· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. C. Kruse

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1 paper

Recent·Most cited

Pharmacology & ToxicologyNature Structural & Molecular BiologyPeer-reviewedOct 5, 2018

Structural basis for sigma-1 receptor ligand recognition

H. R. Schmidt, R. M. Betz, R. O. Dror, A. C. Kruse

This study presents crystal structures and MD simulations of the sigma-1 receptor bound to ligands, revealing agonist-induced structural changes and a multistep binding mechanism.

DOI 10.1038/s41594-018-0137-2

humanstructural biology

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