Cryo-EM structures of the ATP release channel pannexin 1
Z. Deng, Z. He, G. Maksaev, R. M. Bitter, M. Rau, J. A. J. Fitzpatrick, P. Yuan
This study presents cryo-EM structures of pannexin 1 from Xenopus tropicalis and Homo sapiens, revealing its heptameric architecture and molecular sieve mechanism for ATP release.
bioRxiv · Jan 5, 2020Biophysics