Author

R. M. Hughes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. I. Wurz· 1 shared A. R. Cohen· 1 shared C. Dessauges· 1 shared E. M. Szatmari· 1 shared G. F. Hoffmann· 1 shared M. Dobrzynski· 1 shared M.-A. Jacques· 1 shared O. Pertz· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. I. Wurz

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3 papers

Recent·Most cited

CRY-BARs: Versatile light-gated molecular tools for the remodeling of membrane architectures

A. I. Wurz, W. P. Bunner, E. M. Szatmari, R. M. Hughes

This paper introduces CRY-BARs, light-gated I-BAR domain tools for spatial and temporal control of membrane remodeling and cellular dynamics in live cells.

bioRxiv · Jan 28, 2022Cell Biology

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

P. A. Gagliardi, M. Dobrzynski, M.-A. Jacques, C. Dessauges, P. Ender, Y. Blum, R. M. Hughes, A. R. Cohen, O. Pertz

The paper shows ERK/Akt activity waves from apoptotic cells protect neighboring cells and maintain epithelial homeostasis through EGFR and MMP signaling.

bioRxiv · Jun 11, 2020Cell Biology

Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators

W. C. Godwin, G. F. Hoffmann, T. J. Gray, R. M. Hughes

This paper improves an optogenetic system to induce apoptosis and measures the timing of morphological and biochemical changes during early apoptosis.

bioRxiv · Apr 29, 2019Biochemistry