Author

R. M. Irwin

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Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. W. Smyth· 1 shared M. A. Thomas· 1 shared M. D. Mayan· 1 shared M. J. Fahey· 1 shared M. L. Delco· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBioengineering

J. W. Smyth

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1 paper

Recent·Most cited

Connexin 43 Regulates Intercellular Mitochondrial Transfer from Human Mesenchymal Stromal Cells to Chondrocytes

R. M. Irwin, M. A. Thomas, M. J. Fahey, M. D. Mayan, J. W. Smyth, M. L. Delco

This study shows that Cx43 and its isoform GJA1-20k facilitate mitochondrial transfer from mesenchymal stromal cells to chondrocytes, particularly under oxidative stress, suggesting potential therapeutic applications for osteoarthritis.

bioRxiv · Mar 18, 2024Bioengineering