R. M. Thomas

Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function

This study shows Ikaros is essential for Treg function by cooperating with Foxp3 to regulate gene expression and suppress inflammation.

Chromatin conformation dynamics during CD4+ T cell activation implicates autoimmune disease-associated genes and regulatory elements

The paper identifies autoimmune disease-associated genes and regulatory elements by analyzing chromatin dynamics during CD4+ T cell activation using RNA-seq, ATAC-seq, and HiC.