Author

A. D. Wells

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Assay:ATAC-seq· 1

Frequent Co-Authors

C. Su· 2 shared M. C. Pahl· 2 shared M. E. Johnson· 2 shared R. M. Thomas· 2 shared S. F. Grant· 2 shared A. Bar-Or· 1 shared A. Modi· 1 shared A. Naji· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

C. Su

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Author profile →

4 papers

Recent·Most cited

Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function

R. M. Thomas, M. C. Pahl, L. Wang, S. F. Grant, W. W. Hancock, A. D. WELLS

This study shows Ikaros is essential for Treg function by cooperating with Foxp3 to regulate gene expression and suppress inflammation.

bioRxiv · May 23, 2023Immunology

Chromatin conformation dynamics during CD4+ T cell activation implicates autoimmune disease-associated genes and regulatory elements

M. C. Pahl, P. Sharma, R. M. Thomas, Z. Thompson, Z. Mount, J. Pippin, P. A. Morawski, C. Su, D. J. Campbell, S. F. Grant, A. D. Wells

The paper identifies autoimmune disease-associated genes and regulatory elements by analyzing chromatin dynamics during CD4+ T cell activation using RNA-seq, ATAC-seq, and HiC.

bioRxiv · Apr 5, 2023Immunology

Integrative genomics identifies lncRNA regulatory networks across 1,044 pediatric leukemias and extra-cranial solid tumors

A. Modi, G. Lopez, K. L. Conkrite, C. Su, T. C. Leung, S. Ramanan, E. Manduchi, M. E. Johnson, D. Cheung, S. Gadd, J. Zhang, M. A. Smith, J. M. Guidry Auvil, D. S. Gerhard, S. Meshinchi, , S. J. Diskin

The paper identifies lncRNA regulatory networks in pediatric cancers using integrated genomics data from 1,044 samples, revealing their roles in proliferation, metabolism, and DNA damage.

bioRxiv · Dec 10, 2020 · PreprintCancer Biology

The identity of human tissue-emigrant CD8+ T cells

M. Buggert, L. A. Vella, S. Nguyen, V. Wu, T. Sekine, A. Perez-Potti, C. R. Maldini, S. Manne, S. Darko, A. Ransier, L. Kuri-Cervantes, A. Sada Japp, I. Bukh Brody, M. A. Ivarsson, L. Hertwig, , M. R. Betts

The paper characterizes tissue-emigrant CD8+ T cells in humans and non-human primates, revealing distinct migratory behaviors and clonal dynamics.

bioRxiv · Aug 11, 2020Immunology