Biophysical insight into protein-protein interactions in the Interleukin-11/Interleukin-11Rα/glycoprotein 130 signaling complex
C. Mori, S. Nagatoishi, R. Matsunaga, D. Kuroda, M. Nakakido, K. Tsumoto
This study compares the molecular interactions of the IL-11/IL-11R/gp130 complex with IL-6/IL-6R/gp130, revealing differences in thermodynamics and domain involvement that may explain distinct biological functions.
bioRxiv · Jul 14, 2022Biochemistry