Mcm10 functions to isomerize CMG-DNA for replisome bypass of DNA blocks
L. D. Langston, R. Mayle, G. D. Schauer, O. Yurieva, D. Zhang, N. Y. Yao, R. E. Georgescu, M. E. O'Donnell
This study shows Mcm10 enables CMG helicase to bypass DNA blocks on the non-tracking strand by isomerizing the CMG-DNA complex.
bioRxiv · Jun 6, 2017Biochemistry