Author

G. D. Schauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:yeast· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

M. E. O'Donnell· 3 shared O. Yurieva· 2 shared A. E. Shaw· 1 shared A. J. Timmerman· 1 shared A. M. van Oijen· 1 shared C. Kay· 1 shared C. Maher· 1 shared D. Zhang· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiophysics

M. E. O'Donnell

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4 papers

Recent·Most cited

Revised Mechanism of Hydroxyurea Induced Cell Cycle Arrest and an Improved Alternative

A. E. Shaw, J. E. Whitted, M. N. Mihelich, H. J. Reitman, A. J. Timmerman, G. D. Schauer

This paper revises the mechanism of hydroxyurea-induced cell cycle arrest in yeast, showing it is ROS-mediated rather than Mrc1-dependent, and introduces an improved alternative to HU called RNR-deg.

bioRxiv · Mar 2, 2024Biochemistry

Tunability of DNA polymerase stability during eukaryotic DNA replication

J. S. Lewis, L. M. Spenkelink, G. D. Schauer, O. Yurieva, S. H. Mueller, V. Natarajan, G. Kaur, C. Maher, C. Kay, M. E. O'Donnell, A. M. van Oijen

The paper shows how DNA polymerase stability and exchange dynamics in the yeast replisome are tuned by local concentrations, enabling efficient replication and adaptation to genomic challenges.

bioRxiv · Jun 7, 2019Biophysics

Replisome preservation by a single-stranded DNA gate in the CMG helicase

M. R. Wasserman, G. D. Schauer, M. E. O'Donnell, S. Liu

The paper shows CMG helicase opens a single-stranded DNA gate to traverse forked junctions and resume replication after DNA damage, with Mcm10 facilitating this process.

bioRxiv · Jul 13, 2018Biophysics

Mcm10 functions to isomerize CMG-DNA for replisome bypass of DNA blocks

L. D. Langston, R. Mayle, G. D. Schauer, O. Yurieva, D. Zhang, N. Y. Yao, R. E. Georgescu, M. E. O'Donnell

This study shows Mcm10 enables CMG helicase to bypass DNA blocks on the non-tracking strand by isomerizing the CMG-DNA complex.

bioRxiv · Jun 6, 2017Biochemistry