Author

R. Mirzaei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

V. W. Yong· 3 shared C. D'Mello· 2 shared F. Visser· 2 shared P. Bose· 2 shared A. Bohm· 1 shared A. Gerber· 1 shared A. Nikolic· 1 shared B. Wong· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

V. W. Yong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatially resolved single-cell analysis uncovers protein kinase C-& expressing microglia with anti-tumor activity in glioblastoma

R. Mirzaei, R. McNeil, C. D'Mello, B. Wong, S. Sarkar, F. Visser, C. Poon, P. Bose, V. W. Yong

This study identifies PKCδ-expressing microglia with anti-tumor activity in GBM using spatial transcriptomics and confirms their presence in human samples.

bioRxiv · Dec 4, 2023 · PreprintImmunology

Single cell spatial analysis identifies regulators of brain tumor initiating cells

R. Mirzaei, C. D'Mello, M. Liu, A. Nikolic, M. Kumar, F. Visser, P. Bose, M. Gallo, V. W. Yong

The paper identifies biglycan as a regulator of brain tumor initiating cells through spatial transcriptomics and single-cell ATAC-seq, showing its role in Wnt/β-catenin pathway activation and tumor growth.

bioRxiv · Sep 13, 2022Cancer Biology

Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM

A. Bohm, J. DePetro, C. Binding, A. Gerber, N. Chahley, M. Ware, K. Thomas, S. Bukhari, C. Chen, E. Chahley, C. Grisdale, N. D. Berger, S. Lawn, Y. Yu, R. Wong, , G. Cairncross

This study develops a mouse model of glioblastoma (GBM) that replicates its genomic landscape and early stages, enabling research into prevention and treatment strategies.

bioRxiv · Nov 9, 2019 · PreprintCancer Biology