Author

R. N. Das

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

A. Berner· 2 shared E. Chorell· 2 shared M. Doimo· 2 shared S. Wanrooij· 2 shared A. Abrahamsson· 1 shared J. Golebiewska· 1 shared J. L. O. Pohjoismäki· 1 shared K. Aasumets· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

A. Berner

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Author profile →

2 papers

Recent·Most cited

G4-Ligand Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures

A. Berner, R. N. Das, N. Bhuma, J. Golebiewska, A. Abrahamsson, M. Andreasson, N. Chaudhari, M. Doimo, P. P. Bose, K. Chand, R. Stromberg, S. Wanrooij, E. Chorell

The paper develops a method to selectively target and stabilize individual G4 DNA structures using ligand-conjugated oligonucleotides, demonstrating specificity without affecting off-target G4 formations.

bioRxiv · Sep 20, 2023 · PreprintBiochemistry

Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells

M. Doimo, S. Abrahamsson, V. L'Hote, M. Ndi, R. N. Das, K. Aasumets, A. Berner, S. Goffart, J. L. O. Pohjoismäki, M. Davila, E. Chorell, S. Wanrooij

The paper shows that mitochondrial DNA replication stalling increases G-quadruplex formation, which blocks replication forks and leads to mtDNA loss in human cells.

bioRxiv · Jun 8, 2022Cell Biology