Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia
W. F. Richter, R. N. Shah, A. J. Ruthenburg
The paper identifies non-canonical H3K79me2-dependent pathways in MLL-rearranged leukemia that contribute to survival, showing that low-dose pinometostat affects FLT3 and STAT5A signaling.
bioRxiv · Dec 4, 2020Cancer Biology