Hsp47 Promotes Biogenesis of Multi-subunit Neuroreceptors in the Endoplasmic Reticulum
Y.-J. Wang, X.-J. Di, D.-Y. Han, R. Nashmi, B. J. Henderson, F. J. Moss, T.-W. Mu
This study shows Hsp47 enhances GABAA receptor surface expression by binding folded receptors and promoting their assembly and trafficking, with similar effects on other Cys-loop receptors.
bioRxiv · Oct 24, 2022Cell Biology