AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation
W.-C. Lu, R. Omari, H. Ray, I. Williams, C. Jacobs, N. Hockaden, M. L. Bochman, R. L. Carpenter
This study identifies AKT1-mediated phosphorylation events that enhance HSF1 activation, with specific residues critical for trimerization and gene transactivation.
bioRxiv · Aug 31, 2020Biochemistry