R. P. Theart

Three-dimensional mitochondrial fission, fusion and depolarisation event location prediction for a high throughput analysis of fluorescence microscopy images

This paper develops two 3D GANs to predict mitochondrial fission, fusion, and depolarisation events in fluorescence microscopy images, achieving moderate accuracy but indicating potential for future improvements.

DRP1-mediated mitochondrial fission is essential to maintain cristae morphology and bioenergetics

This study investigates how DRP1 mutations affect mitochondrial and peroxisomal dynamics, leading to metabolic dysfunction and structural abnormalities in EMPF1 patient fibroblasts.