Losartan Increases Survival of the Fbn1mgR/mgR Mouse Model of Marfan Syndrome in and Age-Dependent Manner
J. D. Smith, J. Z. Chen, R. Phillip, A. Daugherty, M. B. Sheppard
This study shows that losartan improves survival in male Fbn1mgR/mgR mice when started at 50 days old but not at 24 days, while no benefit was seen in females.
bioRxiv · Feb 19, 2021 · PreprintPhysiology