The M-phase regulatory phosphatase PP2A-B55δ opposes protein kinase A on Arpp19 to initiate meiotic division
T. Lemonnier, E. M. Daldello, R. Poulhe, T. Le, M. Miot, C. Jessus, A. Dupre
The paper identifies PP2A-B55δ as the phosphatase that dephosphorylates Arpp19 at S109, counteracting PKA to release oocytes from meiotic prophase.
bioRxiv · Oct 18, 2019Cell Biology