MicrobiologybioRxiv
Nasal immunization with the C-terminal domain of BclA3 induced specific IgG production and attenuated disease symptoms in mice infected with Clostridioides difficile spores
A. R. Conduto Dias Maia, R. Reyes-Ramírez, M. Pizarro-Guajardo…·D. Paredes-Sabja
This study shows that the C-terminal domain of BclA3 induces IgG production and reduces CDI symptoms in mice, but spore-displayed antigen is less effective.
DOI 10.3390/ijms21186696