Retrieving High-Resolution Information from Disordered 2D Crystals by Single Particle Cryo-EM
R. Righetto, N. Biyani, J. Kowal, M. Chami, H. Stahlberg
The paper develops a method to improve resolution and resolve conformational heterogeneity in 2D crystals using single-particle refinement, achieving 4 Å resolution for the MloK1 potassium channel.
bioRxiv · Feb 26, 2019Biophysics