Treatment with anti-HER2 chimeric antigen receptor tumor-infiltrating lymphocytes (CAR-TILs) is safe and associated with antitumor efficacy in mice and companion dogs
E. M. Forsberg, R. Riise, S. Saellstrom, J. W. Karlsson, S. Alsen, V. Bucher, A. E. Hemminki, R. Olofsson Bagge, L. Ny, L. M. Nilsson, H. Ronnberg, J. A. Nilsson
This study evaluates the safety and antitumor efficacy of anti-HER2 CAR-TILs in mice and dogs, showing tumor eradication and tolerability.
bioRxiv · Sep 11, 2022Cancer Biology