Author

L. Ny

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. A. Nilsson· 4 shared L. M. Nilsson· 3 shared R. Olofsson Bagge· 3 shared S. Alsen· 3 shared V. R. Sah· 3 shared E. M. Forsberg· 2 shared H. Jespersen· 2 shared J. Karlsson· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersCancer Biology

J. A. Nilsson

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4 papers

Recent·Most cited

Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases

J. W. Karlsson, V. R. Sah, R. Olofsson Bagge, I. Kuznetsova, M. Iqba, S. Alsen, S. Stenqvist, A. Saxena, L. Ny, L. Nilsson, J. A. Nilsson

bioRxiv · May 16, 2023Cancer Biology

Treatment with anti-HER2 chimeric antigen receptor tumor-infiltrating lymphocytes (CAR-TILs) is safe and associated with antitumor efficacy in mice and companion dogs

E. M. Forsberg, R. Riise, S. Saellstrom, J. W. Karlsson, S. Alsen, V. Bucher, A. E. Hemminki, R. Olofsson Bagge, L. Ny, L. M. Nilsson, H. Ronnberg, J. A. Nilsson

This study evaluates the safety and antitumor efficacy of anti-HER2 CAR-TILs in mice and dogs, showing tumor eradication and tolerability.

bioRxiv · Sep 11, 2022Cancer Biology

Epigenetic therapy to enhance therapeutic effects of PD-1 inhibition in uveal melanoma

V. R. Sah, H. Jespersen, J. Karlsson, M. Lindberg, L. M. Nilsson, L. Ny, J. A. Nilsson

This study investigates enhancing PD-1 inhibitor efficacy in uveal melanoma through epigenetic modulation with HDAC or BET inhibitors, finding that HDAC inhibition synergizes with immunotherapy.

bioRxiv · Feb 4, 2021Cancer Biology

Molecular profiling of driver events and tumor-infiltrating lymphocytes in metastatic uveal melanoma

J. Karlsson, L. M. Nilsson, E. M. Forsberg, S. Mitra, S. Alsen, G. Shelke, V. R. Sah, U. Stierner, C. All-Eriksson, B. Einarsdottir, H. Jespersen, L. Ny, P. Lindner, E. Larsson, R. Olofsson Bagge, J. A. Nilsson

This study profiles genomic and transcriptomic features of metastatic uveal melanoma, identifying BAP1 inactivation and immune checkpoint receptor expression in tumor-infiltrating lymphocytes.

bioRxiv · Aug 21, 2019Cancer Biology